Bioprocessing Application Notes & Case Studies

  1. MOBIUS® POWER MIX for High Viscosity Solutions

    Mobius® Power MIX is a family of high performance, single-use mixing systems targeted for mixing in biopharmaceutical product/process development and manufacturing and also meets the challenge of blending in high viscosity solutions.

  2. Improved Bioavailability Of Trio Medicines In 12 Weeks

    Learn how a structured 3-step approach can help overcome the challenge of molecular characterization and a limited budget.

  3. Reference Methods For Packing Columns With IMAC Resin: From Lab-Scale to Process Scale

    Reference methods for packing columns with Nuvia IMAC Resin : From Lab-Scale to Process Scale. This collateral details the packing of Nuvia IMAC in 3 different column sizes.

  4. Automated Endotoxin Testing Reduces Errors and Review Time

    Pharmaceutical manufacturers are embracing automation and robotics, mainstays of other manufacturing fields, but can automation and robotics be brought into the QC lab as well?

  5. Automated In-Line Buffer Prep Saves Time And Facility Footprint

    Buffer preparation is both time-and space-consuming and can easily become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-line conditioning (IC).

  6. Overcoming Buffer Challenges With In-Line Conditioning

    How in-line conditioning (IC) can help reduce the number of hold tanks and floor space needed for buffer preparation and storage.

  7. Continuous Chromatography In Downstream Processing Of A Monoclonal Antibody

    In this study, periodic counter current (PCC) chromatography and straight-through processing (STP) technologies were evaluated in a continuous three-step monoclonal antibody (MAb) purification process.

  8. High-Density Vero Cell Perfusion Culture Single-Use Vessels

    Read why Fibra-Cel disks are a promising alternative attachment matrix with a high surface-to- volume ratio and provide a three-dimensional environment that protects cells from damaging shear forces, helping to achieve high cell densities.

  9. Parallel CHO Cell Cultivation In Eppendorf BioBLU c Single-Use Bioreactors

    Parallel operation of multiple bioreactors and the use of single-use equipment can help reducing development times and ultimately costs.

  10. An Innovative Solution To Flexibly Meet Unique Primary Packaging Requirements

    A customer enlisted Catalent to support their child-resistant blister packaging requirements for a global Phase III study. A flexible design was created with an integrated blister card that could also support larger study requirements of 1.9 million monthly dosing cards. Through customized commercial blistering equipment a solution was provided that would accommodate the customer’s growing demands for clinical supplies.