Industry Insights

  1. Mapping The Evolution Of Biomanufacturing

    Processing has evolved thanks to single-use technologies and the next big transformation is on the horizon: continuous bioprocessing.

  2. Novel Uses For Oral Solid Doses Driving Lifecycle Management Strategies

    With few potential blockbuster drugs in the pharma pipeline right now, drug companies are increasingly looking at other options to meet the needs of patients and increase revenue in the oral solid dosage arena.

  3. What Makes A “Good” Bioprocess?

    The development of an optimized bioprocess requires a holistic approach tailored to the specific needs of the product.

  4. Purification Of Recombinant F(Ab’)2 Fragments And Their Various Applications

    Fragment antigen binding domains, or F(ab) fragments, are derived from the upper branches of the ‘Y’-shaped antibody molecule. They form the antigen binding interfaces of intact antibodies.

  5. Microbiology Fulfills A Vital QC Role At A CDMO In Aseptic Filling And Sampling

    Microbiological contamination is at the top of the CDMO threat list. A CDMO needs to have clearly defined procedures and allow client access to data.

  6. Complex Molecule Development: What Should You Consider Early To Avoid Failing Later?

    How to understand and prepare for challenges early in development to avoid bottlenecks that significantly slow production and delay a drug’s time to market.

  7. Tips For Preparing And Using Buffers With Your Chromatography System

    One of the important and often overlooked tips to increase the performance of a chromatography system is to understand how to best use and prepare buffers and solvents.

  8. The Past And Future Of Managing Raw Material And Process Risks In Biomanufacturing

    How far have we come in raw material supply management, and what still needs accomplished to ensure the delivery of safe and effective drugs?

  9. An Efficient Purification Platform For Recombinant Proteins

    Mixed-mode chromatography matrices are designed to present multiple interaction modes to resolve target proteins and impurities, entities that are themselves complex multimodal molecules. 

  10. Evolution Of Single-Use Bioprocessing Into BioPharm 4.0

    Biopharma manufacturers seek dynamic processing economics that address the paradigm shift from blockbuster drugs with established production schemes to small-scale manufacturing and innovative tech.