DOWNSTREAM PROCESSING FEATURED ARTICLES

Tiny Capsule Effectively Kills Cancer Cells
Tiny Capsule Effectively Kills Cancer Cells

A tiny capsule invented at a UCLA lab could go a long way toward improving cancer treatment.

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DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

  • High-Throughput Screening And Process Development For Capture Of Recombinant Pro-Insulin From E. coli
    High-Throughput Screening And Process Development For Capture Of Recombinant Pro-Insulin From E. coli

    This Application note describes a complete process development workflow from PreDictor™ plate screening to a 400 mL pilot-scale purification for capturing recombinant pro-insulin expressed in E. coli.

  • Optimizing A Growth Media Filtration System For Mycoplasma Control
    Optimizing A Growth Media Filtration System For Mycoplasma Control

    Case study on helping a supplier to the biopharmaceutical industry optimize the filtration train they used to sterilize growth media into bioprocess containers while also maintaining Mycoplasma control.

  • USP <787> Small Volume Testing With Liquid Particle Counters
    USP <787> Small Volume Testing With Liquid Particle Counters

    By their very nature, biological therapeutics are not only expensive to manufacture but are often produced in small volumes.

  • Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate
    Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate

    By William Whitford, Strategic Solutions Leader, BioProcess, GE Healthcare Life Sciences

    The industry is abuzz with talk about continuous biomanufacturing (CB), and its virtues have been well described. Here we will look at some of the barriers or concerns perceived to limit its value to the industry. Justified or not, quite a few concerns have been expressed regarding the implementation of this new, rather disruptive technology. 

  • Removal Of Host Cell Proteins During Monoclonal Antibody Purification

    Protein A chromatography is a widely used and highly successful method of purifying recombinant monoclonal antibodies. However, since Protein A has high affinity for antibodies, harsh conditions such as low pH are often required to elute monoclonal antibodies from Protein A affinity columns. By 3M Purification Inc

  • Managing Risk In Biomanufacturing
    Managing Risk In Biomanufacturing

    Commercial, manufacturing, and supply aspects in the biopharmaceutical industry can all be managed in order to mitigate risk. This white paper focuses on how a structured and transparent risk management process can be an ideal way to align the needs of patients with drug manufacturers and their suppliers, regulators, investors, and employees. Read on to learn more about guarding commercial interests, building and managing manufacturing capacity, and preventing supply disruption, and how these things can impact managing risk in biomanufacturing.

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DOWNSTREAM PROCESSING PRODUCTS

Macro-Prep Methyl HIC Media Macro-Prep Methyl HIC Media

Macro-Prep hydrophobic interaction chromatography (HIC) media are methacrylate-based, 50 µm beads used for protein, polypeptide, enzyme, and nucleic acid purification.

Bioreactor Filters - Fluid Clarification Bioreactor Filters - Fluid Clarification
Hydrophilic media and depth filters. Cellulosic, Diatomaceous earth + cellulose, GF, polyproylene and nano fiber disposable capsules or cartridges. For clarification, prefiltration or to protect columns. Many different inlet / outlet connections, with or without vents and drains. SIP / Autoclavable. Specify when gamma stability is required.
Chromatography Columns For Lab Bench Scientists To Biopharma Manufacturers Chromatography Columns For Lab Bench Scientists To Biopharma Manufacturers

We offer empty columns to meet the demands of users from lab bench scientists to biopharmaceutical manufacturers. These easy-to-use columns are suitable for a range of applications. For simplification of screening processes, we also offer 96-well plates designed for collection of eluted samples.

Process Development Process Development

GE Healthcare offers a wide range of filtration and chromatography products, as well as label-free protein interaction systems, and bioreactors for cell expansion.

Armatures & Housings: Prevent Electrode Membrane Damage Armatures & Housings: Prevent Electrode Membrane Damage

All Hamilton General Use Housings/Armatures have an integrated electrode protection design to prevent possible damage of the electrode membrane due to solid components in the sample.

Contract Sterilization Services For Microbial Control

STERIS Isomedix Services provides contract sterilization and microbial control services for single-use bioprocess systems used in the production of biopharmaceuticals and vaccines.

Liquid Chromatography System For Scale-Up Biomanufacturing: ÄKTA Liquid Chromatography System For Scale-Up Biomanufacturing: ÄKTA

ÄKTA ready is a liquid chromatography system built for process scale-up and production for early clinical phases. The system can be used with ready-to-use disposable flow paths, eliminating the need for cleaning between products/batches. Two versions of ÄKTA ready are available: one version for only isocratic use and the other with gradient capability.

1066 Liquid Analytical Transmitter 1066 Liquid Analytical Transmitter

This loop-powered analytical unit serves industrial, commercial and municipal applications with the widest range of liquid measurement inputs available for a two-wire liquid transmitter.

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DOWNSTREAM PROCESSING MULTIMEDIA

Optima X Series Ultracentrifuge: Energy Efficient Technology, Real-Time Data Tracker

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Large Scale Automated Depth Filtration Video

The Zeta Plus Encapsulated System product portfolio for single-use depth filtration has been expanded to include the Model# 16EZC Multi-Round Holder.

GE Healthcare At AAPS: FTA DMPK Cards

Jim Robbins and Julie Hilton Demonstrate GE Healthcare's Whatman Indicating FTA DMPK cards.

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DOWNSTREAM PROCESSING INDUSTRY NEWS

More Downstream Processing Industry News